Acetazolamide Suppresses Multi-Drug Resistance-Related Protein 1 and P-Glycoprotein Expression by Inhibiting Aquaporins Expression in a Mesial Temporal Epilepsy Rat Model.

CONCLUSIONS The present findings confirm that the AQP4 inhibitor, acetazolamide, effectively inhibits the multi-drug-resistant protein, MRP1, and Pgp, in the MTLE rat model. PMID: 29217817 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29217817?dopt=Abstract

Source: Medical Science Monitor - December 9, 2017 Category: Research Tags: Med Sci Monit Source Type: research