Renal Resistive Index as a Novel Indicator for Renal Complications in High-Fat Diet-Fed Mice

Conclusion: This study seems to confirm the utility of a noninvasive and repeatable ultrasound parameter to rapidly evaluate renal fibrosis in a HFD-induced type 2 diabetic mouse modelin vivo. This highly sensitive and comparable renal RI measurement could monitor the whole procedure of disease development in real-time. RI measurement of the renal artery is capable of differentiating responses to standard therapy with lovastatin in HFD-fed mice from the CHD group.Kidney Blood Press Res 2017;42:1128 –1140
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research