Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood-brain barrier dysfunction.

CONCLUSIONS: ProCPU is increased in CSF during hyperacute ischemic stroke and are associated with stroke progression and outcome after 3 months, most likely due to BBB dysfunction in the hyperacute phase of ischemic stroke. This article is protected by copyright. All rights reserved.
PMID: 29194929 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - December 1, 2017 Category: Hematology Authors: Mertens JC, Leenaerts D, Brouns R, Engelborghs S, Ieven M, De Deyn PP, Lambeir AM, Hendriks D Tags: J Thromb Haemost Source Type: research