Novel Survivin-Targeted Small Interfering RNA Delivered by Nanoparticles.

CONCLUSIONS: Our findings revealed that survivin suppression by siRNA may contribute to tumor inhibition through both proliferation inhibition and apoptosis promotion effect, and the pharmacokinetic characteristics serve as a fundamental role for further studies on its applicability for cancer therapy.
PMID: 29173363 [PubMed - in process]

Source: The American Journal of the Medical Sciences - November 1, 2017 Category: General Medicine Authors: Feng C, Wang T, Zhang Y, Qu K, Tang S Tags: Am J Med Sci Source Type: research