Down ‐regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP‐2 and inducing mesenchymal‐to‐epithelial transition

In conclusion, MYOF plays an important role in VM and knockdown of MYOF suppresses VM formation via decreasing MMP‐2 and inducing MET in A375 melanoma cells.

Source: Journal of Cellular and Molecular Medicine - November 22, 2017 Category: Molecular Biology Authors: Wenxue Zhang, Ping Zhou, Ai Meng, Rongxin Zhang, Yan Zhou Tags: Original Article Source Type: research