Perils of sixth sense : SPRINT trial a false GOD in a hypertensive world !

  One big hypertension trial called SPRINT was published in 2015, has caused major delayed aftershocks in the hypertensive world now in 2017. The new guidelines by 2017  AHA/ACC is based primarily on SPRINT data which in my opinion has so much flaws it shouldn’t have been accepted for publication in the first place. !(Intentions and Aim of a study can never be questioned even by most prestigious journals you know !) The flaws begin right  from study design itself. Why diabetic population was excluded from the SPRINT trial is not clearly answered in the true interest of public.The Ironical argument is diabetic patients had no benefit with intensive BP management in ACCORD study. So why waste another study ! Funny is in’t?  When CVD risk profile is intimately linked with these two major entities (DM/HT) it defies sense to  exclude them from the study of population which is going to assess population based  CVD risk reduction. Another dramatic confounder is , 90% of SPRINT patients were taking baseline anti HT drugs. So the original pressure of these people (No,they are patients !) should have been high . (If you apply this logic SPRINT study will not apply for general population who are healthy and free from drug intake! ) SPRINT trial also concluded there is little benefit in Acute MI and renal protection. The main benefit that tilted in favor of sprint was preventing episodes of cardiac failure which was defined by the primitive , subjective , ever unr...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Ethics in Medicine hyperlipidemia wisdom in cardiology acc aha 2017 american hypertension society SPRINT trial Source Type: blogs