The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing ’s sarcoma cell line

In conclusion, our results provide new insights into tenovin-1’s mode of action by demonstrating that it can induce different pathways of cell death.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research