PHGDH is an independent prognosis marker and contributes cell proliferation, migration and invasion in human pancreatic cancer.

CONCLUSIONS: Our data indicated that the expression of PHGDH is increased in pancreatic cancer and is an independent molecular prognostic factor for pancreatic cancer patients. In addition, PHGDH controls cell proliferation, migration and invasion abilities. Therefore, PHGDH could serve as an important prognostic indicator and therapeutic target for pancreatic cancer. PMID: 29128633 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29128633?dopt=Abstract

Source: Gene - November 8, 2017 Category: Genetics & Stem Cells Authors: Song Z, Feng C, Lu Y, Lin Y, Dong C Tags: Gene Source Type: research