The contribution of pain in determining the health status of cancer patients with bone metastases: A secondary analysis of data from three Phase III registration trials

ConclusionsPain/discomfort was the worst‐rated dimension of the EQ‐5D in this population, but the relationship of this item to BPI pain severity was modest, suggesting that the single pain item of the EQ‐5D may be of limited utility in studies for which pain is an endpoint. SignificanceHealth‐status dimensions include more than pain. We examine the contribution of pain severity and pain‐related functional interference in determining the health status of cancer patients with bone metastases. The pain dimension from a health‐status measure may be an inadequate metric in clinical trials/clinical practice when pain is an important outcome.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fejp.1139

Source: European Journal of Pain - October 30, 2017 Category: Anesthesiology Authors: T. R. Mendoza, A. C. Dueck, Q. Shi, H. Ma, J. Zhang, Y. Qian, C. S. Cleeland Tags: Original Article Source Type: research