Candida haemulonii sensu lato: Update of the Determination of Susceptibility Profile in Argentina and Literature Review

AbstractPurpose of reviewThis review summarizes the information available ofCandida haemulonii sensu lato, and updates the in vitro susceptibility profile of the isolates of these species from Argentina.C. haemulonii sensu lato causes fungemia in low frequency in adults and children; however, the knowledge about this emerging yeast is relevant since it is considered as a multi-resistant pathogen.Recent findingsThe discovery of new antifungal molecules, the determination of epidemiological cutoff value and clinical breakpoints for some yeasts of clinical impact, and the update of techniques to determine thein vitro susceptibility profile to yeast have generated some available information, although, forC. haemulonii sensu lato, this information is not always useful for clinical application.SummaryWe determined the susceptibility profile ofC. haemulonii sensu lato strains isolated in Argentina, as a first step to establish the epidemiological cutoff values in our region. We also review the current situation in other countries.

Source: Current Fungal Infection Reports - October 25, 2017 Category: Infectious Diseases Source Type: research