Photocrosslinker technology: An antimicrobial efficacy of cinnamaldehyde cross-linked low-density polyethylene (Cin-C-LDPE) as a novel food wrapper

Publication date: December 2017 Source:Food Research International, Volume 102 Author(s): H.M. Manukumar, S. Umesha In recent years much attention has been devoted to active packaging technologies that offer new opportunities for the food industry and food preservation. The spoilage of food products during post process handling leads to food contamination and causes life-threatening food-borne illness. The methicillin-resistant Staphylococcus aureus (MRSA) 090 is one of the food-borne pathogens associated with food poisoning that leads to an outbreak of perilous human infections worldwide. The development of resistance in bacteria and diffusion of coated synthetic preservatives into food are the major problem in food packaging industries. In the present work, we have developed a new food wrap method by cross-linking cinnamaldehyde on low-density polyethylene (Cin-C-LDPE) using novel photocrosslinker technology. The cinnamaldehyde showed potent antimicrobial activity (145mg/mL of MIC) against MRSA 090 and radical scavenging activity (RSA). The cinnamaldehyde was successfully cross-linked to LDPE and exhibited excellent antibiofilm properties against MRSA090 compared to bare LDPE. This positive interaction of developed Cin-C-LDPE against MRSA090 biofilm was confirmed by SEM and FT-IR studies, and results showed the damaged cell membrane architecture, inturn abridged adherence of MRSA090. The Cin-C-LDPE wrapped chicken, mutton, cheese, and grapes showed 2.5±0.15 log MRSA...
Source: Food Research International - Category: Food Science Source Type: research

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ConclusionThere was an increase in the prevalence of neuroischemic DFU. The Enterobacteriaceae family replaced SA as the most prevalent pathogen in DFI, with an increase in the isolation of gram-negative microorganisms and mixed polymicrobial cultures. Chronic neuroischemic infected ulcers usually present distinct bacterial isolates; knowledge about the most common agents is warranted in order to better select empiric antibiotic therapy.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSION: Culture-negative peritonitis had superior outcomes compared to culture-positive peritonitis except for non-staphylococcal gram-positive peritonitis. PMID: 32063153 [PubMed - in process]
Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research
Publication date: September 2020Source: Materials Today Communications, Volume 24Author(s): Chanon Talodthaisong, Wissuta Boonta, Saengrawee Thammawithan, Rina Patramanon, Nuntaporn Kamonsutthipaijit, James A. Hutchison, Sirinan KulchatAbstractBiomaterial-based hydrogels incorporating antibacterial agents may provide sustainable solutions to biomedical device failures and the prevention of infections. Herein we report guar gum hydrogels, cross-linked with borax and loaded with silver nanoparticles, that are injectable, exhibit rapid self-healing, and show antibacterial properties towards both gram-positive and gram-negativ...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Publication date: Available online 19 February 2020Source: Materials LettersAuthor(s): Yang Jiao, Qian Liu, Jihua ChenAbstractClinically, non-desired osseointegration and bacterial-associated infection are responsible for the failure of titanium (Ti)-based implantation in orthopedic field. Herein, bone morphogenetic protein 2 (BMP2) loaded TiO2 nanotubes (TNT) arrays were fabricated on Ti substrates. Next, bioactive multilayer films of MA-modified gelatin (GelMA) and N-Cl modification poly (N, N’-methylene bis(acrylamide)) (PMAA-Cl) were deposited onto the BMP2-loaded TNT substrates with layer-by-layer (LBL) self-ass...
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: Available online 19 February 2020Source: Materials LettersAuthor(s): Jingxiang Zhang, Shengqian Zhu, Kunkun Song, Zhuoyue Wang, Zongpu Han, Keren Zhao, Zengjie Fan, Xi Zhou, Qiangqiang ZhangAbstractThree-dimensional (3D) graphene/nano-copper scaffolds (rGCSs) was fabricated using a one-step chemical deposition on 3D reduced graphene oxide architecture (rGOA). The nano-copper was conformably grown on the rGOA substrate with a uniform morphology. Due to combined effects between the graphene skeleton and the nano-copper, the rGCSs demonstrated excellent antibacterial properties in the colony counting experim...
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: Available online 19 February 2020Source: The Lancet PsychiatryAuthor(s): Shuai Liu, Lulu Yang, Chenxi Zhang, Yu-Tao Xiang, Zhongchun Liu, Shaohua Hu, Bin Zhang
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
In this study, we have suggested that LysSAP8 could be a potent alternative as a biocontrol agent that can be used to combat MRSA. PMID: 31635440 [PubMed - as supplied by publisher]
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research
Conclusions: We present the most detailed genomic analysis of MRSA isolated in Sri Lanka to date. The analysis identified a PVL-positive ST5-MRSA-IVc that is prevalent among MRSA causing clinical infections in Sri Lanka. Furthermore, this clone was also found among isolates from the United Kingdom and Australia. Introduction Worldwide, Staphylococcus aureus is the primary causative agent of community-acquired skin and soft tissue infections (SSTI) and is an important cause of hospital-associated invasive infections including bacteremia, pneumonia and endocarditis (Bell et al., 2002; David and Daum, 2010). Panton-Va...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Abstract Methicillin‐resistant Staphylococcus aureus (MRSA) is a major cause of severe healthcare‐associated (HA) infections. Although during the last decade the incidence of HA invasive infections has dropped, the incidence of community‐associated MRSA (CA‐MRSA) infections has risen among the general population. Moreover, CA‐MRSA, livestock‐associated MRSA (LA‐MRSA) and HA‐MRSA (HA‐MRSA) can be found in foods intended for human consumption. Several studies from different geographical areas have reported the presence of enterotoxin genes in several MRSA food isolates. Molecular typing studies have reveale...
Source: Letters in Applied Microbiology - Category: Microbiology Authors: Tags: Review Article Source Type: research
The World Health Organization is issuing a warning about a group of deadly bacteria: Recently, the WHO released its first-ever list of “priority pathogens,” a list of antibiotic-resistant bacteria that the organization says pose the greatest threat to human health. The list is divided into three categories: critical-, high- and medium-priority. Three pathogens made it into the critical-priority group. These bacteria are resistant to multiple antibiotics and pose a high risk to people in hospitals and nursing homes, the WHO says. Multidrug-resistant bacteria, sometimes called “superbugs,” are a ...
Source: Science - The Huffington Post - Category: Science Source Type: news
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