HBxAg suppresses cell apoptosis and promotes the secretion of placental hormones in human placental trophoblasts via activation of the EGFR/Akt pathway.

In conclusion, the pEGFR protein was robustly upregulated in HBx-infected human placenta tissues and trophoblast cells. HBx reduces cell apoptosis and promotes the secretion of placental hormones in human placental trophoblast cells via activation of the EGFR/Akt pathway. PMID: 29052908 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29052908?dopt=Abstract

Source: Cell Biology International - October 20, 2017 Category: Cytology Authors: Wang W, Bai G, Zhang Y, Zhang T, Li C, Yuan Y, Liu S, Wang C Tags: Cell Biol Int Source Type: research