Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats

In conclusion, bumetanide promoted post-stroke axonal sprouting together accompanied by an improved behavioral outcome possibly through restoring and maintaining neuronal chloride homeostasis and creating a recovery-promoting microenvironment by overcoming the axonal growth inhibition encountered after cerebral ischemia in rats.
Source: Neuroscience - Category: Neuroscience Source Type: research