Biphasic Renal Sympathetic Response to Hemorrhagic Hypotension in Mice

Conclusion: Hemorrhagic hypotension in anesthetized mice causes biphasic responses of RSNA with an initial increase, followed by a sustained decrease, and a progressive decrease in HR. The initial sympathoexcitation is mediated by carotid sinus baroreceptors, while the later sympathoinhibition and bradycardia are mediated via the TRPV1 signals of vagal afferents.
Source: Shock - Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research