Contemporary Review of Left Bundle Branch Block in the Failing Heart – Pathogenesis, Prognosis, and Therapy

Cardiac resynchronisation therapy (CRT) is a cornerstone in the contemporary management of heart failure. The most effective way of predicting response to this therapy remains electrocardiographic (ECG) criteria of electromechanical dyssynchrony. The left bundle branch block (LBBB) pattern is currently the most robust ECG criterion in predicting improvement in symptoms and reduction in mortality. However, recent studies using three-dimensional (3D) mapping and cardiac magnetic resonance imaging (CMR) have demonstrated heterogeneous left ventricular activation patterns in patients with LBBB.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Review Source Type: research