Croton megalocarpus Hutch. in Tropical Africa: Phytochemistry, Pharmacology and Medicinal Potential

Croton megalocarpus (C. megalocarpus) is widely used as herbal medicine by the local people in tropical Africa. The potential of C. megalocarpus as traditional medicine, the phytochemistry and pharmacological properties of its parts used as traditional medicines are reviewed. The extensive literature survey revealed that C. megalocarpus is traditionally used to treat or manage at least 41 human and animal diseases and ailments. The species is used as herbal medicine for diseases and ailments such as colds, cough, respiratory diseases, fever and malaria, gastro-intestinal tract diseases, wounds, intestinal worms and as ethnoveterinary medicine. Multiple classes of phytochemicals such as alkaloids, clerodane diterpenoids, fatty acids, flavones, flavonoids, glycosides, phenols, reducing sugars, saponins, sterols, tannins and triterpenoids have been isolated from the species. Scientific studies on C. megalocarpus indicate that it has a wide range of pharmacological activities which include antibacterial, antifungal, anti-inflammatory, antinociceptive, antioxidant, molluscicidal, wound healing and Epstein-Barr virus-activating potency.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

Related Links:

A 43-year-old French man presented with fever, arthralgia, headache, night sweats and dry cough, 3 weeks after returning from Brazil. Physical examination was normal. He reported a visit at the botanic garden of Rio de Janeiro during a 7-day-trip. Blood tests revealed lymphocytosis (5.28G/L), C-reactive protein at 50mg/L, and cholestatic hepatitis (ASAT 148UI/L, ALAT 319UI/L, gamma-GT: 523UI/L, alkaline phosphatase: 234UI/L). Microbiological investigations were negative for the following: blood cultures, malaria quick test, Legionella pneumophila, Streptococcus pneumonia antigenuria; serology for HIV, Histoplasma, Brucella...
Source: Travel Medicine and Infectious Disease - Category: Infectious Diseases Authors: Source Type: research
ConclusionsThirty-seven plants commonly used by the tribes of the CRF as anti-infective agents offer perspectives for further research, as the phytochemistry and phytopharmacology for most of these plants have not been published to date.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
By SAURABH JHA Of my time arguing with doctors, 30 % is spent convincing British doctors that their American counterparts aren’t idiots, 30 % convincing American doctors that British doctors aren’t idiots, and 40 % convincing both that I’m not an idiot. A British doctor once earnestly asked whether American physicians carry credit card reading machines inside their white coats. Myths about the NHS can be equally comical. British doctors don’t prostate every morning in deference to the NHS, like the citizens of Oceania sang to Big Brother in Orwell’s dystopia. Nor, in their daily rounds, do the...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: OP-ED Uncategorized AlfieEvans Source Type: blogs
Conditions:   Stunting;   Underweight;   Pneumonia, Pneumocystis;   Cough;   Malaria;   Fever;   Motor Delay Interventions:   Dietary Supplement: Spirulina;   Dietary Supplement: Control Sponsors:   Programme Against Malnutrition;   Hitotsubashi University;   Alliance Forum Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study aims to critically summarize the nutraceutical properties, phytochemistry and pharmacology of VI with a view to provide baseline data required for further investigations on this plant. Relevant information on the nutraceutical and ethnopharmacological properties of VI was collected from established scientific databases such as ScienceDirect, SciFinder, PubMed, Google Scholar, Medline, and SCOPUS. Additionally, books, book chapters and conference papers were also consulted to access other important information. Comparative analysis of the literature revealed that VI is an important neutraceutical plant in east a...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
i Syzygium cordatum is a valuable medicinal plant in the materia medica of east and southern Africa. The aim of this study was to review the botany, medicinal uses, phytochemistry and ethnopharmacological properties of S. cordatum. Relevant literature search was carried out using internet sources such as ACS, Web of Science, Wiley, SpringerLink, Scopus, Mendeley, Google Scholar, Pubmed, SciFinder, BioMed Central, Science Direct and Elsevier. Other literature sources were conference papers, book chapters, books, theses and websites. The leaves, roots, bark and fruits of S. cordatum are used as ethnomedicines against 24 ...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
ConclusionThe incidence of common AEs among patients treated with Inj AS in real-world settings was found to be relatively low. Future studies should consider larger cohorts to document rare AEs as well.ClinicalTrials.gov IdentifierNCT02817919.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research
Conclusion: Our results highlight that scrub typhus infection is an important cause of pyrexia of unknown origin, and active surveillance is necessary to assess the exact magnitude and distribution of the disease. PMID: 29567888 [PubMed - in process]
Source: Indian Journal of Pathology and Microbiology - Category: Pathology Authors: Tags: Indian J Pathol Microbiol Source Type: research
More News: African Health | Antidoxidants | Complementary Medicine | Cough | Drugs & Pharmacology | Flavonoids | Gastroenterology | Herbs | Malaria | Respiratory Medicine | Study | Sugar