Risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutated patients: an evidence-based approach on what women should know

Deleterious mutations in DNA repair pathways, including breast-cancer susceptibility gene 1 (BRCA1) and breast-cancer susceptibility gene 2 (BRCA2) mutation carries, predispose to an elevated risk for several familial tumor types, such as ovarian cancer (OC), breast cancer and prostate cancer [1 –3].

Source: Cancer Treatment Reviews - September 27, 2017 Category: Cancer & Oncology Authors: F. De Felice, C. Marchetti, S. Boccia, A. Romito, C. Sassu, MG. Porpora, L. Muzii, V. Tombolini, P. Benedetti Panici Tags: Controversy Source Type: research