Biomarker Strategy for the Detection and Prediction of Acute Kidney Injury in Patients With Acute Heart Failure

Since the proposal of cardio-renal syndrome, which describes diseases that involve both heart failure (HF) and acute or chronic kidney disease (CKD), kidney damage has become a topic of discussion in patients with acute HF (AHF). However, the mechanisms and pathophysiology of acute kidney injury (AKI) in AHF patients are multi-factorial and still poorly understood. We first reported AKI on admission in patients with AHF. AKI was found to be already involved in approximately 30% of patients with AHF, with the rate increasing to around 70% over the course of hospitalization.

Source: Journal of Cardiac Failure - September 20, 2017 Category: Cardiology Authors: Akihiro Shirakabe, Noritake Hata, Nobuaki Kobayashi, Hirotake Okazaki, Masato Matsushita, Yusaku Shibata, Suguru Nishigoori, Saori Uchiyama, Kuniya Asai, Wataru Shimizu Source Type: research