Highly Sensitive Cardiac Troponin T and N-Terminal Pro-BNP Between Bisoprolol and Carvedilol in Patients With Chronic Heart Failure

The effects of beta blockers on long-term morbidity and mortality have been established in patients with chronic heart failure with reduced left ventricular function. Among various beta blockers, only carvedilol and bisoprolol are approved by Japanese guidelines for treatment of patients with chronic heart failure. Bisoprolol is highly selectivity for the beta-1 receptor, while carvedilol is a non-selective beta blocker with simultaneous alpha receptor antagonist effects. BNP and NT-proBNP are established biomarkers used in the diagnosis and prognosis of chronic heart failure.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research