HLA-Haploidentical Stem Cell Transplant with Pre-Transplant Immunosuppression for Patients with Sickle Cell Disease

• Stem cell transplant can offer a cure for patients with sickle cell disease (SCD)• SCD patients often lack suitable stem cell donors and have high rate of graft failure• Successful haploidentical transplant significantly expands the donor pool for SCD• PTIS with a reduced toxicity regimen provides prompt engraftment and low toxicity
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research