Acromegaly and Cushing's syndrome caused by a neuroendocrine tumor arising within a sacrococcygeal teratoma

Key Clinical Message A 60‐year‐old man with a pre‐existing stable sacrococcygeal teratoma developed acromegaly, ectopic Cushing's syndrome, and 5HIAA secretion. To our knowledge, this represents the first reported case of ACTH and serotonin secretion, and likely GHRH or GH cosecretion, from a sacrococcygeal teratoma in an adult. A 60‐year‐old man with a pre‐existing stable sacrococcygeal teratoma developed acromegaly, ectopic Cushing's syndrome, and 5HIAA secretion. To our knowledge, this represents the first reported case of ACTH and serotonin secretion, and likely GHRH or GH cosecretion, from a sacrococcygeal teratoma in an adult.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fccr3.1148

Source: Clinical Case Reports - September 14, 2017 Category: General Medicine Authors: Tarig Babiker, Efstathia Kyrodimou, Daniel M. Berney, Mark Gurnell, William M. Drake, Antonia Brooke Tags: Case Report Source Type: research