Association of codon 72 polymorphism of p53 with the severity of cervical dysplasia, E6-T350G and HPV16 variant lineages in HPV16-infected women.

CONCLUSION: The oncogenic potential of the virus is increased by the presence of the p53 arg/arg genotype in the Greek population in such a way that the specific protein interaction E6 (L83V)-p53 (Arg-72) can modify an individual's susceptibility to cervical disease.
PMID: 28857739 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - August 31, 2017 Category: Microbiology Authors: Moschonas GD, Tsakogiannis D, Lamprou KA, Mastora E, Dimitriou TG, Kyriakopoulou Z, Kottaridi C, Karakitsos P, Markoulatos P Tags: J Med Microbiol Source Type: research