Microbial Lineages in Sarcoidosis: A Metagenomic Analysis Tailored for Low Microbial Content Samples.

CONCLUSIONS: Metagenomic sequencing revealed enrichment of microbes in single types of sarcoidosis samples, but limited concordance across sample types. Statistical analysis accounting for environmental contamination was essential to avoiding false positives.
PMID: 28846439 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory and Critical Care Medicine - August 28, 2017 Category: Respiratory Medicine Authors: Clarke EL, Lauder AP, Hofstaedter CE, Hwang Y, Fitzgerald AS, Imai I, Biernat W, Rękawiecki B, Majewska H, Dubaniewicz A, Litzky LA, Feldman MD, Bittinger K, Rossman MD, Patterson KC, Bushman FD, Collman RG Tags: Am J Respir Crit Care Med Source Type: research