Genetically predicted 17{beta}-estradiol and systemic inflammation in women: a separate-sample Mendelian randomisation analysis in the Guangzhou Biobank Cohort Study

Conclusions
Endogenous genetically predicted 17β-estradiol reduced low-grade systemic inflammatory markers (white blood cell count and granulocyte count), consistent with experimental and ecological evidence of 17β-estradiol promoting immune response. Replication in a larger sample is required.

Source: Journal of Epidemiology and Community Health - July 3, 2014 Category: Epidemiology Authors: Zhao, J., Jiang, C. Q., Lam, T. H., Liu, B., Cheng, K. K., Kavikondala, S., Zhang, W. S., Leung, G. M., Schooling, C. M. Tags: Smoking and tobacco, Epidemiologic studies, Cohort studies, Health education, Health promotion, Smoking Other topics Source Type: research