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Acromegaly is associated with increased cancer risk: a survey in Italy

It is debated if acromegalic patients have an increased risk to develop malignancies. The aim of the present study was to assess the standardized incidence ratios (SIRs) of different types of cancer in acromegaly on a large series of acromegalic patients managed in the somatostatin analogs era. It was evaluated the incidence of cancer in an Italian nationwide multicenter cohort study of 1512 acromegalic patients, 624 men and 888 women, mean age at diagnosis 45 ± 13 years, followed up for a mean of 10 years (12573 person-years) in respect to the general Italian population. Cancer was diagnosed in 124 patients, 72 women and 52 men. The SIRs for all cancers was significantly increased compared to the general Italian population (expected: 88, SIR 1.41; 95% CI, 1.18–1.68, P
Source: Endocrine-Related Cancer - Category: Endocrinology Authors: Tags: Research Source Type: research

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Abstract Male breast cancer (MBC) accounts for 1% of all breast cancer. Adult obesity and tallness are risk factors for MBC, but the role of adolescent fatness is largely unknown. We aimed to assess the association between body mass index (BMI) in adolescence and the incidence of MBC in a large cohort of 16‐19 year‐old Israeli males. 1,382,093 Jewish Israeli males aged 16‐19 who underwent anthropometric measurements, a General Intelligence Test (GIT) and other examinations during 1967‐2011, were followed up to 31.12.2012 for MBC incidence. Cox proportional hazards models assessed the association between adolescent ...
Source: International Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research
Date: Tuesday, 10 24, 2017; Speaker: Junfang Ji, Professor, Life Science Institute, Zhejiang University; Lei Zhao, Medical Director, Shandong Cancer Hospital/Shandong University; Building: Building 37; 6041/6107
Source: NIH Calendar of Events - Category: American Health Source Type: events
Researchers have found a link between oral sex and smoking and an increased risk of a type head and neck cancer triggered by the human papillomavirus.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
CONCLUSION: Highly expressed proteins in malignant pleural effusion were associated with carcinogenesis and cell growth, and proteins associated with tuberculous pleural effusion played a role in the response to inflammation and fibrosis. These findings will aid in the development of novel diagnostic tools for tuberculous pleurisy and malignant pleural effusion of lung cancer. PMID: 29047238 [PubMed - in process]
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
CONCLUSION: This study provides evidence that PM10 and NO₂ contribute to lung cancer incidence in Korea. PMID: 29047234 [PubMed - in process]
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
CONCLUSION: Our findings provide specific biological roles of miR-191 in ESCC survival and progression. Targeting the novel miR-191/EGR1 axis represents a potential new therapeutic way to block ESCC development. PMID: 29047233 [PubMed - in process]
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
Abstract Gut microbiota play critical physiological roles in energy extraction from the intestine and in the control of systemic immunity, as well as local intestinal immunity. Disturbance of gut microbiota leads to the development of several diseases, such as colitis, inflammatory bowel diseases, metabolic disorders, cancer, etc. From a metabolic point of view, the gut is a large metabolic organ and one of the first to come into contact with dietary fats. Interestingly, excessive dietary fat has been incriminated as a primary culprit of metabolic syndrome and obesity. After intake of high-fat diet or Western diet...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
New J. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7NJ02252B, PaperGangaraju Gedda, Guan-Rong Chen, Yueh-Yun Yao, Wubshet Mekonnen Girma, Jyun-Dong Li, Chia-Liang Yen, Yong-Chien Ling, Jia-Yaw Chang Dual targeting towards cellular receptors specific to the tumor is an important approach for cancer diagnosis. In this work, we demonstrated the aqueous synthesis of Gd3+-doped CuInS2/ZnS (CIGS/ZnS) quaternary quantum... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
In this study, a... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
A California woman claimed she developed ovarian cancer by using Johnson&Johnson talc-based baby powder for feminine hygiene
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
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