New-onset severe hypercholesterolemia in a patient with cholestatic liver disease. Should we treat the lipids?

Aim: Hypercholesterolemia is a common feature of cholestatic liver syndromes. However, cholesterol levels beyond 500 mg/dl rarely occur in patients with cholestasis. The data for other specific types of cholestatic syndromes except for primary biliary cirrhosis is sparse in the literature. The administration of lipid-lowering agents (LLA) in these syndromes is still controversial.

Source: Atherosclerosis - August 1, 2017 Category: Cardiology Authors: Panteleimon Papakonstantinou, Eirini Theodoraki, Mairi Koulentaki, John Papadakis Source Type: research