Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-limb immobilization.

CONCLUSIONS: Moderate-quality evidence showed that the use of LMWH in outpatients reduced DVT when immobilization of the lower limb was required, when compared with no prophylaxis or placebo. The quality of the evidence was reduced to moderate because of risk of selection and attrition bias in the included studies. Low-quality evidence showed no clear differences in PE between the LMWH and control groups, but less symptomatic VTE in the LMWH groups. The quality of the evidence was downgraded due to risk of bias and imprecision.
PMID: 28780771 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - August 6, 2017 Category: General Medicine Authors: Zee AA, van Lieshout K, van der Heide M, Janssen L, Janzing HM Tags: Cochrane Database Syst Rev Source Type: research