Immunosuppressive Treatment in C3 Glomerulopathy: Is it Really Effective

Conclusion: Although patients receiving immunosuppressive treatments had higher proteinuria and lower serum albumin at baseline, there were no differences between these patients and those receiving conservative care alone in proteinuria remission or in the decline of renal function. Younger age, higher proteinuria, lower eGFR, and the presence of crescentic and sclerotic glomeruli, severity of interstitial fibrosis, and no remission of proteinuria predicted the progression of kidney disease.Am J Nephrol 2017;46:96-107
Source: American Journal of Nephrology - Category: Neurology Source Type: research