Does hypothermia impair cerebrovascular autoregulation in neonates during cardiopulmonary bypass?

ConclusionsArterial blood pressure, temperature, and cerebral autoregulation were collinear in this cohort. The conclusion that hypothermia causes impaired autoregulation is thus confounded. The effect of temperature on autoregulation should be delineated before clinical deployment of autoregulation monitors to prevent erroneous determination of optimal arterial blood pressure. Showing the effect of temperature on autoregulation will require a normotensive hypothermic model.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fpan.13194

Source: Pediatric Anesthesia - June 27, 2017 Category: Anesthesiology Authors: Brendan Smith, Eric Vu, Kathleen Kibler, Craig Rusin, Ronald B. Easley, Dean Andropoulos, Jeffrey Heinle, Marek Czosnyka, Daniel Licht, Jennifer Lynch, Ken Brady Tags: RESEARCH REPORT Source Type: research