Typical angina is associated with greater coronary endothelial dysfunction but not abnormal vasodilatory reserve

ConclusionsAmong subjects with CMD and no obstructive CAD, those with TA had more angina pectoris, shortness of breath, and worse quality of life, as well as more severe coronary endothelial dysfunction. Typical angina in the setting of CMD is associated with worse symptom burden and coronary endothelial dysfunction. These results indicate that TA CMD subjects represent a relatively new CAD phenotype for future study and treatment trials.

Source: Clinical Cardiology - May 1, 2017 Category: Cardiology Authors: Ahmed AlBadri, Derek Leong, C. Noel Bairey Merz, Janet Wei, Eileen M. Handberg, Chrisandra L. Shufelt, Puja K. Mehta, Michael D. Nelson, Louise E. Thomson, Daniel S. Berman, Leslee J. Shaw, Galen Cook ‐Wiens, Carl J. Pepine Tags: CLINICAL INVESTIGATIONS Source Type: research