Blood-brain barrier peptide shuttles.

Blood-brain barrier peptide shuttles.
Curr Opin Chem Biol. 2017 May 27;38:134-140
Authors: Sánchez-Navarro M, Giralt E, Teixidó M
Abstract
Brain delivery is hampered by the presence of the blood-brain barrier (BBB), a natural defence of the brain that protects it and allows the entrance of nutrients by several mechanisms. Taking advantage of these mechanisms is an opportunity to treat brain related diseases. Among the different alternatives, BBB peptide shuttles are gaining attention to increase brain delivery of therapeutics. The most recent advances in the field are analysed here.
PMID: 28558293 [PubMed - as supplied by publisher]

Source: Current Opinion in Chemical Biology - May 27, 2017 Category: Biochemistry Authors: Sánchez-Navarro M, Giralt E, Teixidó M Tags: Curr Opin Chem Biol Source Type: research