Efficacy and safety of tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled-release studies.

CONCLUSIONS: The analyses suggest that tapentadol PR provided superior pain relief and a more improved overall health status than oxycodone CR in a large patient population with moderate to severe chronic osteoarthritis pain. Compared to oxycodone CR, tapentadol PR showed a more favourable tolerability profile with better gastrointestinal tolerability. PMID: 28537506 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research