Efficacy and Safety of Rivaroxaban Compared with Warfarin among Elderly Patients with Nonvalvular Atrial Fibrillation in the ROCKET AF Trial.

CONCLUSIONS: -Elderly patients had higher stroke and major bleeding rates than younger patients, but the efficacy and safety of rivaroxaban relative to warfarin did not differ with age, supporting rivaroxaban as an alternative for the elderly. Clinical Trial Registration Information-ClinicalTrials.gov; Unique Identifier: NCT00403767.
PMID: 24895454 [PubMed - as supplied by publisher]

Source: Circulation - June 3, 2014 Category: Cardiology Authors: Halperin JL, Hankey GJ, Wojdyla DM, Piccini JP, Lokhnygina Y, Patel MR, Breithardt G, Singer DE, Becker RC, Hacke W, Paolini JF, Nessel CC, Mahaffey KW, Califf RM, Fox KA, on behalf of the ROCKET AF Steering Committee and Investigators Tags: Circulation Source Type: research