The beneficial hemodynamic effects of afterload reduction by sodium nitroprusside during rewarming from experimental hypothermia.

CONCLUSION: When rewarming the present model of HCD a significant increase in SVR takes place. In this context, pharmacologic intervention aimed at reducing SVR show clear positive results on CO and SV. However, a reduction in SVR alone is not sufficient to fully alleviate CO during HCD, and indicate the need of additional inotropic support. PMID: 28479295 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28479295?dopt=Abstract

Source: Cryobiology - May 4, 2017 Category: Biology Authors: Håheim B, Kondratiev T, Dietrichs ES, Tveita T Tags: Cryobiology Source Type: research