Maternal levels of Epstein-Barr virus IgG antibodies and risk of multiple sclerosis in offspring in the Finnish Maternity Cohort (S44.006)

Conclusions:Elevated maternal levels of VCA IgG are associated with an increased risk of MS in the offspring. Further studies are needed to elucidate potential biological mechanisms.Study Supported by: This study was funded by the National Institute of Neurological Disorders and Stroke (NIH R01 NS073633, PI: Ascherio).Disclosure: Dr. Munger has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. Aivo has nothing to disclose. Dr. Hongell has nothing to disclose. Dr. Soilu-Hanninen has nothing to disclose. Dr. Surcel has nothing to disclose. Dr. Ascherio has received personal compensation for activities with Almirall, Bayer HealthCareRoche, Sanofi-Aventis, and EMD Serono as a speaker. Dr. Ascherio has received research support from National Institutes of Health and the National Multiple Sclerosis Society.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Munger, K., Zhang, Z., Aivo, J., Hongell, K., Soilu-Hanninen, M., Surcel, H.-M., Ascherio, A. Tags: MS Risk Factors and Modifications Source Type: research