A Case Highlighting the Phenotypic Variants Associated with Anti-GQ1B IgG Spectrum Disorders (P6.194)

Conclusions:An emerging condition, acute opthalmoparesis without ataxia and/or areflexia, was described in a handful of publications as "atypical MFS.4" The diagnostic criteria include acute onset of opthalmoplegia, presence of anti GQ1B IgG, and exclusion of other causes3. Other neurological symptoms such as blepharoptosis, bilateral facial paresis, and oropharyngeal palsy have been demonstrated with this condition.4 IVIG and plasmapharesis are not yet a well established treatment5. The diagnosis of acute opthalmoparesis without ataxia and/or areflexia underscores the vast clinical presentations associated with Gq1b spectrum disorders1.Disclosure: Dr. Suresh has nothing to disclose. Dr. Schutt has nothing to disclose. Dr. Tumkur has nothing to disclose. Dr. Suradi has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: General Neurology: Inflammation, Infections, and Autoimmunity Source Type: research