A systematic review and meta-analysis for the adverse effects, immunogenicity and efficacy of Lyme disease vaccines: Guiding novel vaccine development.
CONCLUSION: The current study further validates that the monovalent and multivalent LB vaccines result in mild local side effects and self-limiting systemic adverse effects, with the multivalent vaccine slightly more tolerable than the monovalent one. Both vaccine classes were similarly highly immunogenic. A new vaccine with high safety standards, better efficacy, low cost, and public acceptance is yet to be developed. Meanwhile, personal protection limiting exposure to ticks is recommended.
PMID: 28425901 [PubMed - in process]
Source: Canadian Journal of Public Health - Category: Global & Universal Authors: Badawi A, Shering M, Rahman S, Lindsay LR Tags: Can J Public Health Source Type: research