Does Supplementation with Omega-3 PUFAs Add to the Prevention of Cardiovascular Disease?

AbstractPurpose of ReviewOmega-3 fatty acids are increasingly used for the protection of cardiovascular disease. The main but not the sole mechanism of action is the reduction of triglyceride levels. In this review, we summarize the effect of omega-3 supplements on all-cause and cardiovascular mortality, myocardial infarction, and stroke from the relevant randomized controlled trials.Recent FindingsTwenty-one randomized controlled trials assessed omega-3 supplementation on mortality and cardiovascular-related outcomes. From these studies, as well as from the relevant meta-analyses, we found that omega-3 supplements do not exert a consistent benefit for cardiovascular protection.SummaryThere is uncertainty of a clear profit from omega-3 supplementation in cardiovascular disease.
Source: Current Cardiology Reports - Category: Cardiology Source Type: research