The influence of mean arterial pressure during cardiopulmonary bypass on cerebral complications

Stroke and postoperative cognitive dysfunction are common complications after cardiac surgery. Furthermore, silent strokes detected by diffusion-weighted magnetic resonance imaging (DWI) have been reported in up to 50% of cardiac surgery patients. The majority of these lesions seems to be caused by emboli, but other mechanisms may induce hypoperfusion and consequently lead to tissue ischaemia. A few randomised controlled trials have previously investigated the influence of mean arterial pressure (MAP) during cardiopulmonary bypass (CPB) on cardiac and neurological endpoints with diverging results.

Source: Journal of Cardiothoracic and Vascular Anesthesia - April 1, 2017 Category: Anesthesiology Authors: Anne Gr ønborg Vedel, F Holmgaard, L Rasmussen, A Langkilde, OB Paulson, PS Olsen, T Lange, HB Ravn, JC Nilsson Source Type: research