Incidental findings on brain MRI of cognitively normal first-degree descendants of patients with Alzheimer's disease: a cross-sectional analysis from the ALFA (Alzheimer and Families) project
Conclusions
Brain MRIs of healthy middle-aged participants show a relatively high prevalence of IF even when study participants have been screened for subtle cognitive alterations. Most of our participants are first-degree descendants of patients with AD, and therefore these results are of special relevance for novel imaging studies in the context of AD prevention in cognitively healthy middle-aged participants.
Trial registration number
NCT02198586.
Source: BMJ Open - Category: Journals (General) Authors: Brugulat-Serrat, A., Rojas, S., Bargallo, N., Conesa, G., Minguillon, C., Fauria, K., Gramunt, N., Molinuevo, J. L., Gispert, J. D. Tags: Open access, Neurology, Radiology and imaging Research Source Type: research
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