From Genome Research: Pathogen demonstrates genome flexibility in cystic fibrosis

(Cold Spring Harbor Laboratory) Chronic lung infections can be devastating for patients with cystic fibrosis (CF), and infection by Burkholderia cenocepacia, one of the most common species found in cystic fibrosis patients, is often antibiotic resistant. In a study published today in Genome Research, scientists sequenced and phenotyped multiple B. cenocepacia isolates from 16 CF patients. They found extensive variation among isolates during chronic lung infection as well as changes in clinically relevant bacterial phenotypes.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news