Changes in renal vessels associated with long-term administration of angiotensin converting enzyme inhibitor in Zucker fatty rats.

Conclusions It was indicated that long-term ACEI administration induced unusual proliferative changes in SMCs in afferent arterioles of ZFRs. These changes could reduce intraglomerular pressure by narrowing the lumens of afferent arterioles, but they could cause irreversible damage to the arterioles. PMID: 28260705 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/28260705?dopt=Abstract

Source: Journal of Smooth Muscle Research - March 7, 2017 Category: Research Tags: J Smooth Muscle Res Source Type: research