Make the Diagnosis: Unusual Adenoma

(MedPage Today) -- Case Findings: A 42-year-old male presents with a long history of headaches, impaired vision, and fatigue. He mentions that his wedding ring no longer fits, and he reports joint pain. On physical exam, he has swollen hands and feet, coarse facial features, and partial blindness (bitemporal hemianopsia). After diagnosis with acromegaly secondary to a pituitary macroadenoma, the patient is referred for surgery. However, the patient's IGF-1 concentrations remain elevated following a debulking procedure (the tumor location prevented full resection). What is the best next step for this patient?
Source: MedPage Today Cardiovascular - Category: Cardiology Source Type: news

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Abstract OBJECTIVES: To examine longitudinal symptoms, mobility and function, and quality of life (QOL) in adults newly diagnosed with acute leukemia. SAMPLE & SETTING: 55 adults undergoing induction chemotherapy at the University of North Carolina Lineberger Comprehensive Cancer Center and the Duke Cancer Institute. METHODS & VARIABLES: A prospective, longitudinal study with measures of mobility and function, global physical and mental health, cancer-related fatigue, anxiety, depression, sleep disturbance, pain intensity, and leukemia-specific QOL was conducted. Data were analyzed using descript...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
BACK pain could be caused by having bad posture, sleeping in an awkward position, or by a minor injury. Adding this cheap fruit to your daily breakfast diet cold help to get rid of lower back pain symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 18 August 2018Source: Carbohydrate PolymersAuthor(s): Xianqun Cai, Shengxue Hu, Bangrui Yu, Yilei Cai, Jianmin Yang, Feng Li, Yunquan Zheng, Xianai ShiAbstractPeritoneal adhesion is a general complication following pelvic and abdominal surgery, which may lead to chronic abdominal pain, bowel obstruction, organ injury, and female infertility. Biodegradable polymer membranes have been suggested as physical barriers to prevent peritoneum adhesion. In this work, a transglutaminase (TGase)-catalyzed crosslinked carboxymethyl chitosan/carboxymethyl cellulose/collagen (CMCS/CMCL/COL) composite a...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
This study compared the best corrected visual acuity (BCVA), surgically induced astigmatism (SIA), endothelial cell loss, and patient satisfaction between corneal section phacoemulsification (CSP) and Blumenthal manual small incision cataract surgery (MSICS).MethodsIn this pragmatic study, following pre-operative assessment, patients made a choice to undergo either CSP or MSICS after the options were explained by the ophthalmologist. Pre- and post-operative (Day 1, 1-week, 6-weeks) refraction, keratometry and specular microscopy were performed. Subjective improvement in visual function was assessed before surgery and at 6-...
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
After being told disease would destroy her vision, Paola Peretti wrote a children ’s novel – and found a template for lifePaola Peretti is losing her eyesight and she wouldn ’t have it any other way. When she was 14, she became very short-sighted, virtually overnight. Three years later came the diagnosis ofStargardt macular dystrophy, a degenerative disease that destroys central vision, damages colour perception and results in blindness. Two years ago, finding herself in a place of both “desperation and hope,” the 32-year-old Italian language teacher and debut novelist decided to step out from...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Blindness and visual impairment Books Disability Health Culture Society Psychology Science Life and style & wellbeing Source Type: news
This study aims to evaluate the awareness of testicular torsion amongst Irish parents and evaluate their response to a potential torsion.MethodsAn anonymous questionnaire was distributed to parents attending general paediatric clinics and an acute paediatric unit in two paediatric tertiary referral centres. SPSS statistical analysis software was used to perform multivariant analysis of the data.ResultsThere were 242 completed surveys. Fifty-six percent of responders had an awareness of torsion. In the event of an episode of severe testicular pain parents who were aware of testicular torsion were 4 times more likely to pres...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
AbstractPurposeTo provide latest evidence on the use of suprapubic catheter (SPC) versus urethral catheter (UC) after robot-assisted laparoscopic radical prostatectomy (RARP).Materials and methodsA systematic revision of literature was performed up to September 2017 using different search engines (Pubmed, Ovid, Scopus) to identified studies comparing the use of SPC versus standard UC after RARP. Identification and selection of the studies were conducted according to the preferred reporting items for systematic reviews and meta-analysis criteria. For continuous outcomes, the weighted mean difference (WMD) was used as a summ...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
CONCLUSIONS: Alpha-lipoic acid and spinal cord stimulation were effective for pain; studies were short-term with quality deficits. Spinal cord stimulation had serious adverse events. Further research should address long-term outcomes and other non-pharmacologic treatments. PMID: 30114983 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
uuml;cel Ümide Demir Özkay Atomoxetine is a selective noradrenaline reuptake inhibitor drug. Based on the knowledge that agents increasing monoamine levels in the central nervous system have therapeutic potential for neuropathic pain, it is planned to investigate the possible efficacy of atomoxetine on diabetes-induced hyperalgesia, in this study. Randall-Selitto (mechanical noxious stimuli) and Hargreaves (thermal noxious stimuli) tests were used to evaluate nociceptive perception of rats. Obtained data indicated that streptozotocin-induced diabetes causes significant decreases in the paw withdrawal thresh...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Dear Carol: I’m not yet 30 and struggling with family caregiving. I work an entry level job that barely pays my rent and student loan payment. I love my mom and grandma, but I hadn’t expected this responsibility so soon. Mom was taking care of Grandma who’s had dementia for years but then Mom had a stroke. I’m an only child so there are no siblings to help. My dad’s not involved with us. Grandma’s in a nursing home. According to the doctors, Mom’s condition isn’t expected to improve a whole lot from where she is now which means she will continue to need a wheelchair... R...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
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