Abstract P3-13-02: Impact of primary surgery on short-term survival of older breast cancer patients in the UK

Conclusions:ctDNA analysis identified PIK3CA mutations in pts with previously unknown or WT mutation status from archival tumor tissue; ORR and CBR were similar to those from archival tumor tissue suggesting that PIK3CA mutation testing from ctDNA may be used as a surrogate when tissue is unavailable. 21.7% of pts had mutations in both ESR1 and PIK3CA.Citation Format: Bundred N, Lavelle K, Sowerbutts AM, Pilling M, Todd C. Impact of primary surgery on short-term survival of older breast cancer patients in the UK [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P3-13-02.

Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: N Bundred, K Lavelle, AM Sowerbutts, M Pilling, C Todd Tags: Poster Session Abstracts Source Type: research