Optimization of initial propofol bolus dose for EEG Narcotrend Index ‐guided transition from sevoflurane induction to intravenous anesthesia in children

ConclusionAfter sevoflurane induction, a reduced propofol bolus dose of 1 mg·kg−1 followed by TIVA according to McFarlan's regime resulted in a NI within the recommended range in children aged 1–8 years. During the course of TIVA, children younger than 2 years displayed higher NI values and more pronounced interindividual variation. Processed EEG monitoring is recommended to find adequate individual age‐dependent doses.

Source: Pediatric Anesthesia - January 31, 2017 Category: Anesthesiology Authors: Nils Dennhardt, Dietmar Boethig, Christiane Beck, Sebastian Heiderich, Martin Boehne, Andreas Leffler, Barbara Schultz, Robert S ümpelmann Tags: Research Report Source Type: research