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Is it depression or dementia? Brain SPECT imaging helps distinguish them

(IOS Press) Does a patient have depression or a cognitive disorder (CD) such as Alzheimer's disease or both? Since both disorders have overlapping symptoms, how can a clinician tell them apart to make an appropriate diagnosis? In a new article published in the Journal of Alzheimer's Disease, researchers have found that single photon emission computed tomography, or SPECT, can help to distinguish between these diagnostic categories.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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One of the most important things I learned as an Alzheimer's caregiver was how to use bright light to change my mother's mood and behavior.By Bob DeMarcoAlzheimer's Reading RoomMy mother, Dotty, had a tendency to get in a bad mood around 4:30 PM each day. It was like a form of sundowning. Learn more about that situation by following this link.Twilight Moments in Dementia Patients - Sundowning SyndromeShe might say things like I'm going to bed,or something much worse.What really struck me was the look on her face. It seemed like she wasn't there; or, sometimes like she as very unhappy. I didn't like the look on her face and...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: Alzheimers Dementia alzheimers reading room bright light bright light alzheimers care of dementia patients how to learning Source Type: blogs
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The presence of a psychiatric comorbidity can significantly affect adherence to buprenorphine. These trends illustrate the need for clinicians treating opioid use disorder with buprenorphine to screen for psychiatric disorders and monitor their medication adherence. There may also be opportunities to design interventions to help this vulnerable population adhere to buprenorphine and other forms of opioid pharmacotherapy. (Am J Addict 2017;XX:1-5). PMID: 29143483 [PubMed - as supplied by publisher]
Source: American Journal on Addictions - Category: Addiction Authors: Tags: Am J Addict Source Type: research
AbstractThe emergence of complement as an important player in normal brain development and pathological remodelling has come as a major surprise to most scientists working in neuroscience and almost all those working in complement. That a system, evolved to protect the host against infection, should have these unanticipated roles has forced a rethink about what complement might be doing in the brain in health and disease, where it is coming from, and whether we can, or indeed should, manipulate complement in the brain to improve function or restore homeostasis. Complement has been implicated in diverse neurological and neu...
Source: Seminars in Immunopathology - Category: Pathology Source Type: research
The essential role played by the hippocampus within the human brain makes it a particularly important target for neuroimaging studies. The hippocampus is well known for its functional involvement in the mechanisms of memory and has also been associated with various diseases or conditions through its very structure, either directly in memory-related disorders such as Alzheimer's Disease (Bobinski et al., 1999; Jack et al., 1999; Laakso et al., 1996; Reiman et al., 1998; Schuff et al., 2009; Šimić et al., 1997) and PTSD (Bonne et al., 2001; Gilbertson et al., 2002; Gurvits et al., 1996; Pederson et al., 2004; Shin et...
Source: Medical Image Analysis - Category: Radiology Authors: Source Type: research
A study in rats finds that drugs that stop brain cell death may offer a new way to treat those with Alzheimer's who have depression with cognitive decline.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
It takes lots of thought, hard work, and the development of a new mental construct of communication and behavior to understand Alzheimer's disease.By Bob DeMarcoAlzheimer's Reading RoomIt takes lots of thought, hard work, and the development of a new mental construct of communication and behavior to understandAlzheimer's disease. It takes time.Take the relationship between my mother and me as an example.Topic -Alzheimer's Care Living in Alzheimer's WorldI've known my mother my entire life. We have been communicating our entire lives. I would imagine that our communication is similar to most people. We engaged in all the hu...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer alzheimer care alzheimer information Alzheimer World Alzheimer's Communication Alzheimer's Dementia Alzheimer's support group dementia care dementia help for caregivers health Source Type: blogs
Publication date: Available online 26 October 2017 Source:Epilepsy & Behavior Author(s): Andres M. Kanner, Helen Scharfman, Nathalie Jette, Evdokia Anagnostou, Christophe Bernard, Carol Camfield, Peter Camfield, Karen Legg, Ilan Dinstein, Peter Giacobe, Alon Friedman, Bernd Pohlmann-Eden Epilepsy is a neurologic condition which often occurs with other neurologic and psychiatric disorders. The relation between epilepsy and these conditions is complex. Some population-based studies have identified a bidirectional relation, whereby not only patients with epilepsy are at increased risk of suffering from some of these neur...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Abstract BACKGROUND: Great effort has been put into developing simple and feasible tools capable to detect Alzheimer's disease (AD) in its early clinical stage. Spatial navigation impairment occurs very early in AD and is detectable even in the stage of mild cognitive impairment (MCI). OBJECTIVE: The aim was to describe the frequency of self-reported spatial navigation complaints in patients with subjective cognitive decline (SCD), amnestic and non-amnestic MCI (aMCI, naMCI) and AD dementia and to assess whether a simple questionnaire based on these complaints may be used to detect early AD. METHOD: In t...
Source: Current Alzheimer Research - Category: Neurology Authors: Tags: Curr Alzheimer Res Source Type: research
CONCLUSION: Findings suggest that sleep disturbance, depression, and anxiety are associated with AD development among cognitively asymptomatic participants. Decreasing the threat posed by psychological symptoms may be one avenue for possibly delaying onset of AD. PMID: 29077487 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - Category: Geriatrics Authors: Tags: Aging Ment Health Source Type: research
Sadly, even after years of work to educate the public about any illness that affects the brain, a stigma remains. No matter that most, if not all, mental illnesses have a biological basis. No matter that people aren’t any more responsible for a brain illness than they are for other illnesses. The fact remains that whether the disease affects the brain occurs at a younger age in the form of depression or bipolar disease or an older age in the form of Alzheimer’s disease or another dementia, people with brain illnesses are often reluctant to acknowledge their illness for fear of being treated differently than oth...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
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