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Is it depression or dementia? Brain SPECT imaging helps distinguish them

(IOS Press) Does a patient have depression or a cognitive disorder (CD) such as Alzheimer's disease or both? Since both disorders have overlapping symptoms, how can a clinician tell them apart to make an appropriate diagnosis? In a new article published in the Journal of Alzheimer's Disease, researchers have found that single photon emission computed tomography, or SPECT, can help to distinguish between these diagnostic categories.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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Conclusion: A relevant reduction of AD and VaD cases in Europe and Italy could be obtained through primary prevention.Dement Geriatr Cogn Disord Extra 2018;8:60 –71
Source: Dementia and Geriatric Cognitive Disorders Extra - Category: Geriatrics Source Type: research
Statistics indicate as many as 24 percent of Alzheimer's patients wake up caregivers at night and have trouble sleeping.By Bob DeMarcoAlzheimer's Reading RoomRecently I received several emails about sleeping problems.Specifically, about Alzheimer's patients staying up at night, or Alzheimer's patients waking up the caregiver at night.Some doctors recommend antipsychotic medications for this problem.This is completely inappropriate and should be avoided. See -Antipsychotic Medications Linked to Increased Risk of Pneumonia in Alzheimer ’s Patients.Sleep Medications for Alzheimer's and Dementia PatientsStatistics indica...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's care Alzheimer's Dementia alzheimer's sleep dementia care dementia help for caregivers family caregiving help alzheimer's help with dementia care memory care Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Here I'll point out two papers, one looking at exercise and the aging of grey matter in the brain, the other looking at exercise and the aging of white matter in the brain. It is well known that cardiovascular health is linked to cognitive health. An entire category of neurodegenerative disease is related to the age-related failure of the cardiovascular system to remain intact and supply adequate nutrients to the brain. A sizable portion of cognitive decline is linked to incidences of rupture of tiny blood vessels in the brain, each killing a comparatively small number of cells, but over the years that damage adds up. Furt...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Abstract OBJECTIVE: To validate the Rowland Universal Dementia Assessment Scale for use in Brazil (RUDAS-BR). METHODS: We first completed an English-Brazilian Portuguese translation and back-translation of the RUDAS. A total of 135 subjects over 60 years of age were included: 65 cognitively healthy and 70 with Alzheimer's disease (AD) according to the DSM-IV and Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria. All participants completed an interview and were screened for depression. The receiver operating characteristic curves o...
Source: Revista Brasileira de Psiquiatria - Category: Psychiatry Authors: Tags: Rev Bras Psiquiatr Source Type: research
I had to put my life on hold when I decided to take responsibility for my mother. After 8 years of care giving, I found great emotional reward in caring for her. However, I met other caregivers that were clearly suffering from the experience.byAlzheimer's Reading RoomAstudy of spouses ofdementia patients at Case Western Reserve University found that:Some caregivers may have feelings of guilt about participating in activities with friends or in the community when their loved ones are no longer able to do soCaregivers report feelings ofsadness and loneliness25 percent of caregivers in the study suffered fromdepressionand, on...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer Alzheimer spouses Alzheimer's support group alzheimers disease Dementia Patients loneliness medical science mental health sadness Source Type: blogs
Studies indicate that forty percent of the population might be at risk of a vitamin B12 deficiency.By Bob DeMarcoAlzheimer's Reading RoomVitamin B12 deficiency can cause memory loss, dementia like symptoms, does cause shrinkage in the brain, and can cause mean and challenging behavior.Learn More -Care of Dementia PatientsSeveral years ago I started reading up on all the B vitamins. I learned vitamin B12 deficiency is wide spread especially among the elderly. It is easy to understand why. If you don't eat foods that are rich in vitamin B12 you won't get enough into your body.Subscribe to the Alzheimer's Reading - This is a ...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimers care dementia care dementia help for caregivers family caregiving help alzheimer's help with dementia help with dementia care memory care homes vitamin b12 deficiency symptom Source Type: blogs
Authors: Pluta R, Ułamek-Kozioł M, Januszewski S, Czuczwar SJ Abstract Cardiac arrest, usually occurring in the aged population, is the most important cause of high morbidity and death in developed countries. Commonly, attention, depression, cognitive impairment, spatial memory, short- and long-term memory, executive functions, decreased quality of life and social participation are disturbed following circulation arrest. Deficits in cognitive function, similar to prodromal Alzheimer's disease dementia, following cardiac arrest remain an area of concern. Recent research has focused on the post-resuscitation period...
Source: Folia Neuropathologica - Category: Neurology Tags: Folia Neuropathol Source Type: research
Authors: Chiu I, Piguet O, Diehl-Schmid J, Riedl L, Beck J, Leyhe T, Holsboer-Trachsler E, Kressig RW, Berres M, Monsch AU, Sollberger M Abstract OBJECTIVE: Misdiagnosis of early behavioral variant frontotemporal dementia (bvFTD) with major depressive disorder (MDD) is not uncommon due to overlapping symptoms. The aim of this study was to improve the discrimination between these disorders using a novel facial emotion perception task. METHOD: In this prospective cohort study (July 2013-March 2016), we compared 25 patients meeting Rascovsky diagnostic criteria for bvFTD, 20 patients meeting DSM-IV criteria for MD...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Abstract BACKGROUND: The accurate clinical characterisation of mild cognitive impairment (MCI) is becoming increasingly important. The aim of this study was to compare the neuropsychiatric symptoms and cognitive profile of MCI with Lewy bodies (MCI-LB) with Alzheimer's disease MCI (MCI-AD). METHODS: Participants were ⩾60 years old with MCI. Each had a thorough clinical and neuropsychological assessment and 2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane single photon emission computed tomography FP-CIT SPECT). MCI-LB was diagnosed if two or more diagnostic features of dementia with...
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
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