Claimed effects, outcome variables and methods of measurement for health claims proposed under european community regulation 1924/2006 in the framework of protection against oxidative damage and cardiovascular health

The high number of negative opinions from the European Food Safety Authority (EFSA) to the requests for authorization of health claims is largely due to the design of human intervention studies, including the inappropriate choice of outcome variables (OVs) and of their methods of measurement (MMs). The present manuscript reports the results of an investigation aimed to collect, collate and critically analyse the information in relation to claimed effects, OVs and MMs, in the context of protection against oxidative damage and cardiovascular health compliant with Regulation 1924/2006.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 11, 2017 Category: Nutrition Authors: D. Martini, S. Rossi, B. Biasini, I. Zavaroni, G. Bedogni, M. Musci, C. Pruneti, G. Passeri, M. Ventura, S. Di Nuzzo, D. Galli, P. Mirandola, M. Vitale, A. Dei Cas, R.C. Bonadonna, D. Del Rio Source Type: research