Helius Medical touts data from multiple sclerosis pilot study of PONS system

Helius Medical Technologies said today that clinical data from a multiple sclerosis pilot study of its portable neuromodulation stimulator was published in the Multiple Sclerosis Journal: Experimental, Translational and Clinical. The company’s PONS system is designed to treat neurological symptoms, caused by trauma or disease, non-invasively through the tongue. Helius’ pilot study evaluated its PONS device combined with intensive cognitive and physical rehabilitation on working memory, gait, balance and concomitant changes in the brains of patients with MS. The study enrolled 14 patients – 7 used the PONS device and 7 received a sham stimulation. For 14 weeks, patients underwent functional-MRI, motor performance measures and sensory organization tests before and after intense physical therapy and working memory training. The group that used the PONS system showed significant improvement in sensory organization tests and functional-MRI showed signficiant blood oxygen level-dependent signal changes in the left primary motor cortex. The control group had increased activity in bilateral premotor corices, the authors wrote. While all participants improved on working-memory tasks, the group that received Helius’ stimulator showed increased dorsolateral prefrontal cortex activity. The authors concluded that in this group of MS patients, the PONS system enhanced motor performance and working memory, while also encouraging neuroplasticity. “We would lik...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Clinical Trials Neurological Neuromodulation/Neurostimulation Research & Development Helius Medical Technologies Source Type: news