PFO closure: End of an era or beginning of a new chapter?

Key Points This large long‐term retrospective cohort study shows that percutaneous patent foramen ovale (PFO) closure is safe. Higher rates of recurrent stroke or TIA were noted in older patients (age>55) and those with diabetes and hypertension Randomized trials have failed to show significant benefit from PFO closure for cryptogenic stroke though pooled analyses and longer‐term follow‐up have revealed significant reduction in recurrent strokes. Future studies and longer‐term follow‐up will need to elucidate which subgroups of patients will benefit from closure.
Source: Catheterization and Cardiovascular Interventions - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Editorial Comment Source Type: research