Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice [Neuroscience]

White matter stroke is a distinct stroke subtype, accounting for up to 25% of stroke and constituting the second leading cause of dementia. The biology of possible tissue repair after white matter stroke has not been determined. In a mouse stroke model, white matter ischemia causes focal damage and adjacent...

Source: Proceedings of the National Academy of Sciences - December 26, 2016 Category: Science Authors: Elif G. Sozmen, Shira Rosenzweig, Irene L. Llorente, David J. DiTullio, Michal Machnicki, Harry V. Vinters, Lief A. Havton, Roman J. Giger, Jason D. Hinman, S. Thomas Carmichael Tags: PNAS Plus Source Type: research